1 Scope
2 Normative references
3 Terms and definitions
3.1 Differential mobility analyzing system (DMAS)
3.1.1 Differential electrical mobility classifier
(DEMC)
3.1.2 Condensation particle counter (CPC)
3.2 Inhalation chamber system (chamber, head
only, nose only)
3.3 Evaporation/condensation nanoparticle
generator system
4 Principle
4.1 Generation
4.2 Preparation of system
5 Requirements
5.1 Capacity and control
5.2 Nanoparticle properties
5.3 Chamber atmosphere
5.4 System operational safety
6 Characterization of generator performance
7 Nanoparticle generation specifications
7.1 Chemical purity
7.2 Size range
7.3 Number concentration
7.4 Nanoparticle shape
7.5 Stability
7.6 Animal exposure
8 Assessment of results
9 Test report
Annex A (Informative) - Example method for
evaporation/condensation generation of
silver nanoparticles
A.8 Stability of silver nanoparticle generation
and maintenance of concentrations during
day inhalation toxicity study
A.9 Generation of other metal nanoparticles
(e.g. Gold)