• 18/30329940 DC : DRAFT FEB 2018

    Current The latest, up-to-date edition.

    BS ISO 20046 - RADIOLOGICAL PROTECTION - PERFORMANCE CRITERIA FOR LABORATORIES USING FLUORESCENCE IN SITU HYBRIDIZATION (FISH) TRANSLOCATION ASSAY FOR ASSESSMENT OF OVEREXPOSURE TO IONIZING RADIATION

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    Published date:  28-03-2018

    Publisher:  British Standards Institution

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    Table of Contents - (Show below) - (Hide below)

    Foreword
    Introduction
    1 Scope
    2 Normative references
    3 Terms and definitions
    4 Translocation assay by FISH
    5 Responsibility of the customer
    6 Responsibility of the laboratory
    7 Confidentiality of personal information
    8 Laboratory safety requirements
    9 Sample Processing
    10 Background levels of translocations
    11 Calibration Curves
    12 Criteria for converting a measured aberration
       frequency into an estimate of absorbed dose
    13 Reporting of results
    14 Quality assurance and quality control
    Annex A (informative) - Sample instructions for customer
    Annex B (informative) - Sample questionnaire
    Annex C (informative) - Sample of report
    Annex D (informative) - Sample data sheets for recording
            painted aberrations
    Annex E (informative) - Fitting of the dose response-curve
            by the method of maximum likelihood and calculating
            the uncertainty of the absorbed dose estimate
    Annex F (informative) - Process for dose estimation
    Bibliography

    General Product Information - (Show below) - (Hide below)

    Comment Closes On
    Committee NCE/2
    Document Type Draft
    Publisher British Standards Institution
    Status Current

    Standards Referencing This Book - (Show below) - (Hide below)

    ISO/IEC 17025:2005 General requirements for the competence of testing and calibration laboratories
    ISO 13528:2015 Statistical methods for use in proficiency testing by interlaboratory comparison
    ISO 19238:2014 Radiological protection — Performance criteria for service laboratories performing biological dosimetry by cytogenetics
    ISO 11929:2010 Determination of the characteristic limits (decision threshold, detection limit and limits of the confidence interval) for measurements of ionizing radiation Fundamentals and application
    ISO/IEC Guide 98-3:2008 Uncertainty of measurement — Part 3: Guide to the expression of uncertainty in measurement (GUM:1995)
    ISO 17099:2014 Radiological protection Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry
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