• I.S. EN ISO 20046:2021

    Current The latest, up-to-date edition.

    Radiological protection - Performance criteria for laboratories using Fluorescence In Situ Hybridization (FISH) translocation assay for assessment of exposure to ionizing radiation (ISO 20046:2019)

    Available format(s):  Hardcopy, PDF

    Language(s):  English

    Published date:  28-02-2021

    Publisher:  National Standards Authority of Ireland

    For Harmonized Standards, check the EU site to confirm that the Standard is cited in the Official Journal.
    Only cited Standards give presumption of conformance to New Approach Directives/Regulations.

    Dates of withdrawal of national standards are available from NSAI.

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    Table of Contents - (Show below) - (Hide below)

    Foreword
    Introduction
    1 Scope
    2 Normative references
    3 Terms and definitions
    4 Translocation assay by FISH
    5 Responsibility of the customer
    6 Responsibility of the laboratory
    7 Confidentiality of personal information
    8 Laboratory safety requirements
    9 Sample processing
    10 Background levels of translocations
    11 Calibration curves
    12 Criteria for converting a measured aberration frequency into an estimate of absorbed dose
    13 Reporting of results
    14 Quality assurance and quality control
    Annex A (informative) Sample instructions for customer
    Annex B (informative) Sample questionnaire
    Annex C (informative) Sample of report
    Annex D (informative) Sample data sheets for recording painted aberrations
    Annex E (informative) Fitting of the dose response-curve by the method of maximum likelihood and calculating the uncertainty of the absorbed dose estimate
    Annex F (informative) Process for dose estimation
    Bibliography

    Abstract - (Show below) - (Hide below)

    The purpose of this document is to provide criteria for quality assurance (QA), quality control (QC) and evaluation of the performance of biological dosimetry by cytogenetic service laboratories.

    General Product Information - (Show below) - (Hide below)

    Committee TC 85
    Document Type Standard
    Product Note The date of any NSAI previous adoption may not match the date of its original CEN/CENELEC document.
    Publisher National Standards Authority of Ireland
    Status Current
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