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Method for analysis of allergens - Quantification of an extended list of 57 suspected allergens in ready to inject fragrance materials by gas chromatography mass spectrometry
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Available format(s): Hardcopy, PDF
Language(s): English
Published date: 28-05-2021
Publisher: National Standards Authority of Ireland
For Harmonized Standards, check the EU site to confirm that the Standard is cited in the Official Journal.Only cited Standards give presumption of conformance to New Approach Directives/Regulations.Dates of withdrawal of national standards are available from NSAI.
European foreword Introduction 1 Scope 2 Normative references 3 Terms and definitions 4 Principle 5 Reagents 6 Apparatus 7 Stock and sample solutions - preparation and storage 8 Mass spectrometer acquisition conditions 9 Sample analysis 10 Data validation and treatment 11 Test report Annex A (informative) Determination of calibrant and reference sample purity Annex B (informative) GC capillary column parameters Annex C (informative) SIM Ions for SIM or SIM-SCAN UseAnnex D (informative) Example of SIM windows Annex E (informative) Example of chromatograms Annex F (normative) Decisional tree for quantification of suspected allergens Annex G (informative) Preparation of stock solutions from reference samples Annex H (informative) Calibration methods and approach Annex I (informative) Quantification of allergens Annex J (informative) Suspected allergens selected as analytes targets – Rationale Annex K (informative) Other general informationBibliography
The present method permits the identification and quantification of the volatile compounds suspected as allergens, which are present in the fragrance compounds and fragrance raw materials used in cosmetic products.
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