ISO 4126-3:2006 specifies the requirements for a product assembled from the in-series combination of safety valves or CSPRS (controlled safety pressure relief systems) according to ISO 4126-1, ISO 4126-4 and ISO 4126-5, and bursting disc safety devices according to ISO 4126-2 installed within no more than five pipe diameters from the valve inlet. It specifies the design, application and marking requirements for such products, which are used to protect pressure vessels, piping or other enclosures from excessive pressure, and which comprise the bursting disc safety device, a safety valve or CSPRS and, where applicable, a short length of connecting pipe or spool piece. In addition, it gives a method for establishing the combination discharge factor used in sizing combinations.