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18/30329940 DC : DRAFT FEB 2018

Current

Current

The latest, up-to-date edition.

BS ISO 20046 - RADIOLOGICAL PROTECTION - PERFORMANCE CRITERIA FOR LABORATORIES USING FLUORESCENCE IN SITU HYBRIDIZATION (FISH) TRANSLOCATION ASSAY FOR ASSESSMENT OF OVEREXPOSURE TO IONIZING RADIATION

Published date

28-03-2018

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Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Translocation assay by FISH
5 Responsibility of the customer
6 Responsibility of the laboratory
7 Confidentiality of personal information
8 Laboratory safety requirements
9 Sample Processing
10 Background levels of translocations
11 Calibration Curves
12 Criteria for converting a measured aberration
   frequency into an estimate of absorbed dose
13 Reporting of results
14 Quality assurance and quality control
Annex A (informative) - Sample instructions for customer
Annex B (informative) - Sample questionnaire
Annex C (informative) - Sample of report
Annex D (informative) - Sample data sheets for recording
        painted aberrations
Annex E (informative) - Fitting of the dose response-curve
        by the method of maximum likelihood and calculating
        the uncertainty of the absorbed dose estimate
Annex F (informative) - Process for dose estimation
Bibliography

BS ISO 20046.

Committee
NCE/2
DocumentType
Draft
PublisherName
British Standards Institution
Status
Current

ISO/IEC 17025:2005 General requirements for the competence of testing and calibration laboratories
ISO 13528:2015 Statistical methods for use in proficiency testing by interlaboratory comparison
ISO 19238:2014 Radiological protection — Performance criteria for service laboratories performing biological dosimetry by cytogenetics
ISO 11929:2010 Determination of the characteristic limits (decision threshold, detection limit and limits of the confidence interval) for measurements of ionizing radiation Fundamentals and application
ISO/IEC Guide 98-3:2008 Uncertainty of measurement — Part 3: Guide to the expression of uncertainty in measurement (GUM:1995)
ISO 17099:2014 Radiological protection — Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry

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