This Standard specifies requirements for open-fronted laminar flow cytotoxic drug safety cabinets which are intended to provide protection for personnel, the environment, and cytotoxic drug products. These cabinets may also find wider application for handling other hazardous drugs and materials (see AS 2639). They are primarily designed to contain aerosols, and are not intended to provide complete protection against particles which may be ejected during procedures such as tablet crushing and grinding. This Standard should be read in conjunction with AS 2639 which describes recommended practices for installation and use of these cabinets. NOTE: Ergonomic considerations for the design and use of cytotoxic drug safety cabinets are addressed in Appendix A.