BS ISO 10130:2009
Current
The latest, up-to-date edition.
Cosmetics. Analytical methods. Nitrosamines. Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC, post-column photolysis and derivatization
Hardcopy , PDF
English
30-06-2010
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Foreword
Introduction
1 Scope
2 Principle
3 Reagents
4 Apparatus
5 Sample preparation and storage
6 Procedure
7 Calculation of results
8 Test report
Annex A (informative) - Examples of calibration curves
and typical chromatograms
Annex B (normative) - Photolysis and reaction of nitrite
with Griess reagent to form the azo dye
Annex C (normative) - Configuration of the post-column
reactor system
Bibliography
Specifies a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by high performance liquid chromatography (HPLC) coupled with post-column photolysis and derivatization.
| Committee |
CW/217
|
| DevelopmentNote |
Supersedes 08/30174283 DC. (07/2010)
|
| DocumentType |
Standard
|
| Pages |
24
|
| PublisherName |
British Standards Institution
|
| Status |
Current
|
| Supersedes |
This International Standard describes a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by high performance liquid chromatography (HPLC) coupled with post-column photolysis and derivatization.
This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA, nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.
If a product has the possibility of either NDELA contamination from the ingredients or NDELA formation by the composition of ingredients, the method will be applied for the testing of cosmetic products and is an alternative to ISO15819.
This method is not applicable to matrices containing oxidation dyes.
| Standards | Relationship |
| ISO 10130:2009 | Identical |
| ISO 15819:2014 | Cosmetics Analytical methods Nitrosamines: Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC-MS-MS |
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