BS ISO 22303:2008
Current
The latest, up-to-date edition.
Tobacco. Determination of tobacco specific nitrosamines. Method using buffer extraction
Hardcopy , PDF
English
31-03-2009
Important note : Users cannot be edited or removed once added to your Multi user PDF.
Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Reagents
6 Apparatus
7 Preparation of extraction solution and standards
7.1 Preparation of buffer extraction solution
7.2 Preparation of internal standard
7.3 Preparation of calibration standards
7.4 Setting up of the gas chromatograph and detector
7.5 Tobacco extraction and isolation of TSNAs
7.6 Extract concentration
8 Data analysis and calculation of results
9 Repeatability and reproducibility
10 Test report
Annex A (informative) - Typical chromatograms and
calibration curves
Bibliography
Describes the procedure for the determination of the tobacco specific nitrosamines (TSNAs): N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in ground leaf tobacco, manufactured tobacco and tobacco products.
| Committee |
AW/40
|
| DevelopmentNote |
Supersedes 07/30160967 DC. (03/2009)
|
| DocumentType |
Standard
|
| Pages |
20
|
| PublisherName |
British Standards Institution
|
| Status |
Current
|
| Supersedes |
This International Standard specifies the procedure for the determination of the tobacco specific nitrosamines (TSNAs): N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in ground leaf tobacco, manufactured tobacco and tobacco products. The determination is by means of gas chromatography.
| Standards | Relationship |
| ISO 22303:2008 | Identical |
| ISO 1042:1998 | Laboratory glassware — One-mark volumetric flasks |
| ISO/TS 22304:2008 | Tobacco Determination of tobacco specific nitrosamines Method using alkaline dichloromethane extraction |
| ISO 3696:1987 | Water for analytical laboratory use — Specification and test methods |
Access your standards online with a subscription
Features
-
Simple online access to standards, technical information and regulations.
-
Critical updates of standards and customisable alerts and notifications.
-
Multi-user online standards collection: secure, flexible and cost effective.