CLSI C49 P : 1ED 2006

Abstract
Committee Membership
Foreword
1 Scope
2 Standard Precautions
3 Terminology
  3.1 Glossary of Body Fluids
  3.2 Definitions
4 Matrix Effects on Clinical Laboratory Measurements
  4.1 Scientific Basis
  4.2 External Survey Data
5 Pathogenesis and Composition of Accumulation Fluids
  5.1 Amniotic
  5.2 Cerebrospinal Fluid
  5.3 Serous Fluids
  5.4 Synovial
6 Clinically Significant Analyses in Body Fluids
  6.1 Creatinine
  6.2 Amylase/Lipase
  6.3 Bilirubin
  6.4 Total Protein/Albumin
  6.5 Triglycerides
  6.6 Cholesterol
  6.7 Tumor Antigens/Markers
  6.8 Electrolytes
  6.9 pH
7 Recommendations for Alternate Sample Types Not Specified
  in Manufacturers' Claims
  7.1 Elements of Method Verification
  7.2 Assessing Body Fluid Determinations for Validity
  7.3 Precondition
  7.4 Considerations for Use of Tests for Body Fluids Other
      Than Those for Which the Methods Have Been Formally
      Validated
  7.5 Clinically Unique Samples
  7.6 Result Reporting
References
The Quality System Approach
Related CLSI/NCCLS Publications

Provides guidance for the application of widely available measurement procedures for testing body fluids and for reporting and interpreting those results. It emphasizes defining the common clinical situations for this use; acceptable practice for measuring analyses without extended method verification for abnormal body fluid; influence of biologic and analytic variation on interpretation of results; and variability in comparing results between different instrument manufacturers.