CLSI M31 P : 1994

Abstract
Committee Membership
Active Membership
Foreword
1 Introduction
     1.1 Performance Standards for Disk Diffusion Antimicrobial
             Susceptibility Tests for Bacteria that Grow Aerobically
     1.2 Performance Standards for Dilution Antimicrobial
             Susceptibility Tests for Bacterial that Grow Aerobically
2 Selection of Antimicrobial Agents for Routine Testing and Reporting
     2.1 Routine and Selective Reporting
     2.2 Nonproprietary Names
     2.3 Selection Guidelines
     2.4 Guidelines for Routine Reporting
     2.5 Guidelines for Selective Reporting
     2.6 Interpretive Categories
3 Disk Diffusion Susceptibility Testing
     3.1 Indications for Performing Disk Diffusion Susceptibility
             Tests
     3.2 Interpretation
     3.3 Methodologies
4 Broth and Agar Dilution Susceptibility Testing
     4.1 Indications for Performing Broth and Agar Dilution
             Susceptibility Tests
     4.2 Methodologies
5 Quality Control Guidelines
     5.1 Purpose
     5.2 Quality Control Responsibilities
     5.3 Agar Disk Diffusion Tests
     5.4 Dilution Susceptibility Tests
     5.5 Suggested Reference Strains
     5.6 Common Sources of Error
6 Beta-Lactamase Tests
     6.1 Purpose
7 Limitations of Disk Diffusion and Dilution Methods
8 Cumulative Antimicrobial Susceptibility Profile
Tables
Table 1. Suggested Groupings of Therapeutic Antimicrobial Agents for
           Systematic Use That Should Be Considered for Routine Testing
           By Veterinary Microbiology Laboratories
Table 2. Zone Diameter Interpretive Standards and Minimum Inhibitory
           Concentration (MIC) Breakpoints for Veterinary Pathogens
Table 3. Control Limits for Monitoring Antimicrobial Disk
           Susceptibility Test with Veterinary Pathogens; Zone
           Diameter (mm) Limits for Individual Tests on Mueller-Hinton
           Medium without Blood or Other Supplements
Table 3A. Acceptable Zone Diameter (mm) Quality Control Limits for
           Haemophilus somnus and Actinobacillus pleuropneumoniae
Table 4. Control Limits for Monitoring MICs with Veterinary
           Pathogens-Acceptable Quality Control Ranges of MICs for
           Reference Strains
Table 4A. Acceptable Quality Control Ranges of Minimum Inhibitory
           Concentrations (MICs) for Haemophilus somnus and
           Actinobacillus pleuropneumoniae
Table 5. Suggested Modifications of Standard Methods for
           Susceptibility Testing for some Fastidious and
           Special Problem Veterinary Pathogens
Table 6. Solvents and Diluents for Preparation of Stock Solutions
           of Antimicrobial Agents Requiring Solvents Other Than
           Water
Table 7. Scheme for Preparing Dilutions of Antimicrobial Agents
           to be Used in Agar Dilution Susceptibility Tests
References
Appendix: Antimicrobial Susceptibility Quality Control Record
Summary of Comments and Subcommittee Responses
Related NCCLS Publications
 

Contains current recommended techniques for disk and dilution susceptibility testing, criteria for quality control testing, and tables for interpretive criteria for veterinary use.