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CLSI M39 A4 : 4ED 2014

Superseded

Superseded

A superseded Standard is one, which is fully replaced by another Standard, which is a new edition of the same Standard.

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ANALYSIS AND PRESENTATION OF CUMULATIVE ANTIMICROBIAL SUSCEPTIBILITY TEST DATA

Superseded date

10-06-2022

Superseded by

CLSI M39 ED5:2022

Published date

25-08-2018

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Abstract
Committee Membership
Foreword
1 Scope
2 Introduction
3 Standard Precautions
4 Terminology
5 Information System Design
Part I - The Routine Cumulative Antibiogram
6 Data Analysis
7 Data Presentation
8 Use of Cumulative Antimicrobial Susceptibility Reports
9 Limitations of Data, Data Analysis, and Data Presentation
10 Statistical Considerations
Part II - The Enhanced Antibiogram
11 Stratifying Cumulative Antibiogram data by Various
   Parameters
12 Supplemental Analyses of Multidrug-Resistant Organisms
13 Examining Percent Susceptible for Combinations of
   Antimicrobial Agents
14 Analysis of Susceptibility Profiles of Select Organisms
15 Calculating Percent Susceptible on Select Groups of
   Organisms
16 Graphic Presentation of Percent Susceptible Data
   to Illustrate Trends in Susceptibility
17 Local Cumulative Antibiograms vs External Antibiograms
   (eg, Data From External Surveillance Programs)
References
Additional References
Appendix A - Suggestions for Confirmation of Resistant (R),
             Intermediate (I), or Nonsusceptible (NS)
             Antimicrobial Susceptibility Test Results
             and Organism Identification
Appendix B - Rationale Behind the 'First Isolate per Patient'
             Analysis Recommendation
Appendix C - Example of Using a Line Listing to Verify
             Susceptibility Rates Determined by the
             Analysis Software
Appendix D - Examples of Supplemental Analyses - Stratifying
             Cumulative Antibiogram Data by Various Parameters
Appendix E1 - Cumulative Antimicrobial Susceptibility Report
              Example - Antimicrobial Agents Listed
              Alphabetically (Hypothetical Data)
Appendix E2 - Cumulative Antimicrobial Susceptibility Report -
              Antimicrobial Agents Listed by Class
              (Hypothetical Data)
Appendix F - Examples of Graphs to Illustrate Trends in
             Susceptibility
Appendix G - Steps for Presenting Local Cumulative Antibiogram
             Report to Health Care Professionals
Appendix H - Statistical Methods for Examining Percent
             Susceptible
Appendix I - Glossaries of Beta-Lactams and Non-Beta-Lactams:
             Class and Subclass Designation and Generic Name,
             and Abbreviations/Routes of Administration/Drug
             Class for Antimicrobial Agents
Appendix J - Intrinsic Resistance
The Quality Management System Approach
Related CLSI Reference Materials

Specifies methods for recording and analysis of antimicrobial susceptibility test data, consisting of cumulative and ongoing summaries of susceptibility patterns of clinically significant microorganisms.

DevelopmentNote
Supersedes CLSI M39 A3. (02/2014)
DocumentType
Miscellaneous Product
PublisherName
Clinical Laboratory Standards Institute
Status
Superseded
SupersededBy
Supersedes

CLSI M100 S25 : 25ED 2015 PERFORMANCE STANDARDS FOR ANTIMICROBIAL DISK SUSCEPTIBILITY TESTS
CLSI M100 S26 : 26ED 2015 PERFORMANCE STANDARDS FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING

CLSI M44 A2 : 2ED 2009 METHOD FOR ANTIFUNGAL DISK DIFFUSION SUSCEPTIBILITY TESTING OF YEASTS<br>
CLSI M45 A2 : 2ED 2010 METHODS FOR ANTIMICROBIAL DILUTION AND DISK SUSCEPTIBILITY TESTING OF INFREQUENTLY ISOLATED OR FASTIDIOUS BACTERIA
CLSI M38 A2 : 2ED 2008 REFERENCE METHOD FOR BROTH DILUTION ANTIFUNGAL SUSCEPTIBILITY TESTING OF FILAMENTOUS FUNGI
CLSI M29 A3 : 3ED 2005 ACQUIRED INFECTIONS; APPROVED GUIDELINE
CLSI M7 A9 : 9ED 2011 METHODS FOR DILUTION ANTIMICROBIAL SUSCEPTIBILITY TESTS FOR BACTERIA THAT GROW AEROBICALLY
CLSI M27 A3 : 3ED 2008 REFERENCE METHOD FOR BROTH DILUTION ANTIFUNGAL SUSCEPTIBILITY TESTING OF YEASTS
CLSI M11 A8 : 8ED 2012 METHODS FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING OF ANAEROBIC BACTERIA
CLSI M23 A3 : 3ED 2008 DEVELOPMENT OF IN VITRO SUSCEPTIBILITY TESTING CRITERIA AND QUALITY CONTROL PARAMETERS
CLSI M27 S4 : 4ED 2012 REFERENCE METHOD FOR BROTH DILUTION ANTIFUNGAL SUSCEPTIBILITY TESTING OF YEASTS
CLSI M2 A11 : 11ED 2011 PERFORMANCE STANDARDS FOR ANTIMICROBIAL DISK SUSCEPTIBILITY TESTS
CLSI M100 S24 : 24ED 2014 PERFORMANCE STANDARDS FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING

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