CLSI NBS04 : 2ED 2017

Abstract
Committee Membership
Foreword
Chapter 1 - Introduction
Chapter 2 - Overview of Newborn Screening by Tandem
            Mass Spectrometry
Chapter 3 - Reagents, Internal Standards, and Sample Preparation
Chapter 4 - Mass Spectrometer Instrument Considerations
Chapter 5 - Sample Analysis for Newborn Screening Disorders
Chapter 6 - Result Interpretation and Reporting
Chapter 7 - Conclusion
Chapter 8 - Supplemental Information
References
Appendix A - Common Metabolic Disorders: Organic Acid
             Disorders, Fatty Acid Oxidation Disorders, and
             Aminoacidopathies
Appendix B - Metabolites Measured by Tandem Mass
             Spectrometry: Amino Acids
Appendix C - Metabolites Measured by Tandem Mass
             Spectrometry: Acylcarnitines
Appendix D - Preparation of Extraction Solution
Appendix E - Scan Speed Consideration
Appendix F - In-House Control Preparation
Appendix G - Flow Path Blockages
Appendix H - Tubing Considerations
Appendix I - Troubleshooting Guides
Appendix j - Non-Recommended Tandem Mass
             Spectrometry Assays
The Quality Management System Approach
Related CLSI References Materials