DIN EN 16418 E : 2014
Current
The latest, up-to-date edition.
PAPER AND BOARD - DETERMINATION OF THE CYTOTOXICITY OF AQUEOUS EXTRACTS USING A METABOLICALLY COMPETENT HEPATOMA CELL LINE (HEPG2)
30-09-2014
National foreword<br>National Annex NA (informative) - Bibliography<br>Foreword<br>1 Scope<br>2 Normative references<br>3 Terms and definitions<br>4 Principle<br>5 Reagents<br>6 Cell line<br>7 Food simulants used for testing<br>8 Cleaning laboratory glassware<br>9 Equipment<br>10 Preparation of specimens<br>11 Cytotoxicity assessment<br>12 Expression of the results<br>13 Interpretation of the results<br>14 Precision<br>15 Test report<br>Annex A (informative) - 96-well plates configuration<br>Annex B (informative) - RNA Synthesis rate inhibition<br> cytotoxicity test work flow<br>Annex C (informative) - Validation of the two methods<br> (option A and B)<br>Bibliography
Defines a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line.
DocumentType |
Standard
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PublisherName |
German Institute for Standardisation (Deutsches Institut für Normung)
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Status |
Current
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Standards | Relationship |
EN 16418:2014 | Identical |
EN 645:1993 | Paper and board intended to come into contact with foodstuffs - Preparation of a cold water extract |
EN 15845:2010 | Paper and board - Determination of the cytotoxicity of aqueous extracts |
ISO 3696:1987 | Water for analytical laboratory use — Specification and test methods |
EN ISO 3696:1995 | Water for analytical laboratory use - Specification and test methods (ISO 3696:1987) |
EN 647:1993 | Paper and board intended to come into contact with foodstuffs - Preparation of a hot water extract |
DIN ISO 3696:1991-06 | WATER FOR ANALYTICAL LABORATORY USE - SPECIFICATION AND TEST METHODS |
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