AS 2252.2-2004

1 - AS 2252.2-2004 BIOLOGICAL SAFETY CABINETS - LAMINAR FLOW BIOLOGICAL SAFETY CABINETS (CLASS II) FOR PERSONNEL...
4 - PREFACE
6 - CONTENTS
7 - FOREWORD
9 - 1 SCOPE
9 - 2 REFERENCED DOCUMENTS
10 - 3 GENERAL REQUIREMENTS
14 - 4 CONSTRUCTION REQUIREMENTS
14 - 4.1 General
14 - 4.2 Outer shell
14 - 4.3 Work zone
14 - 4.3.1 General
14 - 4.3.2 Viewing windows
14 - 4.3.3 Work access opening
15 - 4.3.4 Work access opening cover
15 - 4.3.5 Work zone illumination
15 - 4.3.6 Work floor
15 - 4.3.7 Grilles
15 - 4.3.8 Sump
15 - 4.4 Filters and filter installations
16 - 4.5 Blowers and alarm systems
16 - 4.5.1 Blowers
16 - 4.5.2 Blower alarm systems
16 - 4.6 Access panels
17 - 4.7 Electrical services
17 - 4.8 Germicidal ultraviolet (UV) lamps
17 - 4.9 Gas supply
18 - 4.10 Adsorbent filter
18 - 4.11 Post-use overrun control
18 - 4.12 Decontamination covers
18 - 5 PERFORMANCE REQUIREMENTS
18 - 5.1 General
18 - 5.2 Critical for cabinet function
18 - 5.2.1 Filter installation integrity
18 - 5.2.2 Air barrier containment
18 - 5.2.3 Work zone integrity
19 - 5.2.4 Air velocity and uniformity in the work zone
19 - 5.2.5 Alarm operational adjustment
19 - 5.3 Vibration
19 - 5.4 Other requirements
19 - 5.4.1 Sound level
19 - 5.4.2 Lighting
19 - 5.4.3 Ultraviolet radiation
20 - 6 MARKING
21 - APPENDIX A - ERGONOMICS
21 - A1 GENERAL
21 - A2 CONSIDERATIONS OF ERGONOMICS FOR SAFETY CABINETS AND ISOLATORS
21 - A2.1 General
22 - A2.2 Design
23 - A2.3 Purchase and use

Specifies general construction and performance requirements for Class II laminar flow biological safety cabinets intended to provide protection for hazardous biological agents for personnel and the environment and also to protect material used in the cabinet from exogenous contamination.

This Standard specifies basic requirements for Class II laminar flow biological safety cabinets that are intended to provide protection from hazardous biological agents for personnel and the environment and also to protect material used in the cabinet from exogenous contamination. The cabinets provide protection by inducing an inflow of room air through the work access opening, by delivering recirculated, high efficiency particulate air (HEPA) filtered, laminar flow air downwards through the work zone and by HEPA filtration of exhaust air. It is essential that this Standard be read in conjunction with AS/NZS 2647 which describes recommended practices for installation and use of these cabinets. NOTES: 1 These cabinets are intended only for handling materials which can be inactivated or rendered safe by an effective decontamination procedure such as that described in AS/NZS 2647. 2 Additional design requirements may apply to cabinets which are required to afford protection against other hazards such as toxic materials not of biological origin or against radiation.3 For work with cytotoxic drugs the user is referred to AS 2567.4 Ergonomic considerations for the design and selection of biological safety cabinets are addressed in Appendix A.

First published as AS 2252.2-1980.
Second edition 1985.
Third edition 1994.
Fourth edition 2004.