CLSI M48 A : 1ED 2008

Abstract
Committee Membership
Foreword
1 Scope
2 Safety and Standard Precautions
  2.1 Risk Assessment
  2.2 Biosafety Levels-General
  2.3 Additional Aspects of Biosafety Pertinent to
      Mycobacteriology
3 Levels of Laboratory and Referral Services
4 Clinical Significance of Mycobacterium spp.
  4.1 Clinical Setting/Pathogenicity
  4.2 Laboratory Indicators
5 Specimen Types, Collection, Transport, and Storage
6 Specimen Processing
7 Detection of Mycobacteria
  7.1 Microscopy
  7.2 Nucleic Acid Amplification Tests (NAATs) for Direct
      Detection of MTBC in Clinical Specimens
  7.3 Detection of Mycobacteria by Culture
8 Identification Procedures
  8.1 Phenotypic Methods
  8.2 Genotypic Methods
  8.3 Rapid Identification of M. tuberculosis Complex With
      Immunochromatography
References
Appendix A - Final Rule, Department of Transportation (DOT)
             Pipeline and Hazardous Materials Safety
             Administration, Hazardous Materials: Infectious
             Substances; Harmonization With the United Nations
             Recommendations. 7 June 2006
Appendix B - Methods for Digestion and Decontamination
Appendix C - Staining Procedures
Appendix D - Preparation and Storage of Quality Control (QC)
             Organisms
Appendix E - Biochemical Procedures
Summary of Delegate Comments and Committee Responses
The Quality Management System Approach
Related CLSI Reference Materials

Describes guidance to clinical mycobacteriology laboratories on the most optimum approach for the diagnosis of mycobacterial infections.