BS ISO 21243:2008

Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Abbreviated terms
5 Pre-planning
   5.1 Awareness of the standard
   5.2 Roles and responsibilities of health care facilities
   5.3 Roles and responsibilities of the biodosimetry laboratories
6 Communication and information
   6.1 Biological dosimetry request and confidentiality
   6.2 Educational programme - Formation, training and exercises
7 Biological dosimetry process in radiological or nuclear
   mass-casualty incidents
8 Emergency response of the reference laboratory
9 Design of laboratory network
   9.1 Overview
   9.2 Preparedness of the laboratory network
   9.3 Laboratory network operation
10 Expected results
   10.1 General
   10.2 Whole-body exposure
   10.3 Inhomogeneous exposure
11 Quality assurance and quality control
   11.1 Overview
   11.2 Quality control
Annex A (normative) - Interactions between physicians and biological
        dosimetry laboratories
Annex B (informative) - Initial contact information form
Annex C (informative) - Guidance for threshold of detection
Annex D (informative) - Estimates of dose and 95% confidence limits
        for selected observations of numbers of dicentrics and cells
Annex E (informative) - Instructions for customers
Annex F (informative) - Example group sample report
Bibliography

Provides an overview of the minimum requirements of process and quality-control components of the cytogenetic response for triage of mass casualties.

The purpose of this International Standard is to give an overview of the minimum requirements of process and quality-control components of the cytogenetic response for triage of mass casualties. Cytogenetic triage is the use of chromosome damage to evaluate approximately and rapidly radiation doses received by individuals in order to supplement the early clinical categorization of casualties. This International Standard concentrates on organizational aspects of applying the dicentric assay for operation in a triage mode. The technical aspects of the dicentric assay can be found in ISO19238. This International Standard is applicable either to an experienced biological dosimetry laboratory working alone or to a network of collaborating laboratories (as defined in Clause9).